The Secret Sauce Behind High-Enrolling PIs

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Sponsors often assume slow enrollment is a patient identification problem. But despite bigger recruitment campaigns, enrollment rates continue to stagnate. The real challenge lies at the screening and enrollment stage – where PI prioritization, site bandwidth, and sponsor support have everything to do with how many patients actually make it onto a study.

In this candid discussion, Dr. Marat Fudim, Duke cardiologist and PI on numerous active studies, joins Dr. Bimal Shah, cardiologist, former Duke research leader, and health-tech executive, for a conversation moderated by John St. Clair of TruTechnologies. Together, they’ll reveal the “secret sauce” that sets high-enrolling investigators apart – and what sponsors can do to better support PIs and the teams behind them.

You’ll gain a clearer understanding of:

The Misalignment Problem: Why volume-based incentives not only fail to fix enrollment, but also create costly downstream consequences.

The PI + Team Equation: Why even the most motivated investigator can’t succeed without dedicated research time and a strong support team of coordinators and staff.

What Motivates High Performers: Why the right mix of motivators – from building their professional reputation to sponsor-side champions who get things done (“Mikes”) – makes all the difference in enrollment success.

Tailoring by Site Type: Why sponsors need to move beyond one-size-fits-all approaches and recognize that what works at an academic center may not work at a community or commercial site.

If you want to understand what really drives PIs to enroll – and how to design incentives that turn identified patients into participants – this conversation is for you.